14
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T36382 | all-trans-5,6-epoxy Retinoic Acid | ||
all-trans-5,6-epoxy Retinoic Acid can be used in related research in the field of life sciences. Its product number is T36382 and CAS number is 13100-69-1. | |||
T7408 | all-trans-4-Oxoretinoic acid | all-trans 4-Keto Retinoic Acid | Endogenous Metabolite |
all-trans-4-Oxoretinoic acid (all-trans 4-Keto Retinoic Acid) is an active metabolite of vitamin A. | |||
T1051 | Retinoic acid | Vitamin A acid,ATRA,all-trans-Retinoic acid,Tretinoin | Retinoid Receptor , Endogenous Metabolite , PPAR , Autophagy |
Retinoic acid (Tretinoin), a metabolite of vitamin A, is a natural agonist of the retinoic acid receptor RAR and inhibits RARα/β/γ (IC50=14 nM). Retinoic acid induces cellular differentiation, reduces cellular proliferat... | |||
T67921 | Retinoic acid-d5 | all-trans-Retinoic acid-d5,Isotretinoin-d5,Vitamin A acid-d5,Accutane-d5,ATRA-d5 | Retinoid Receptor |
Retinoic acid-d5 (Vitamin A acid-d5) is the deuterium-labeled form of Retinoic acid. Retinoic acid is a natural RAR receptor agonist with an IC50 of 14 nM for RARα/β/γ and a Kd of 17 nM for PPARβ/δ. Retinoic acid, a meta... | |||
T6694 | Tamibarotene | NSC 608000,Am 80,Amnolake | Apoptosis , Retinoid Receptor , Autophagy |
Tamibarotene (Amnolake) is an orally active, synthetic retinoid, developed to overcome all-trans retinoic acid (ATRA) resistance, with potential antineoplastic activity. | |||
T7370 | Talarozole | R115866 | Others , P450 , Retinoid Receptor , Autophagy |
Talarozole (R115866) is an oral systemic all-trans retinoic acid metabolism blocking agent (RAMBA). Talarozole inhibits both CYP26A1 and CYP26B1 with IC50s of 5.4 and 0.46 nM, respectively.Talarozole for the treatment of... | |||
T35952 | all-trans Retinoyl β-D-Glucuronide | ||
all-trans Retinoyl β-D-glucuronide is a metabolite of all-trans retinoic acid formed by the UDP-glucuronosyltransferase (UGT) system. It is rapidly converted to all-trans retinoic acid following in vitro or in vivo admin... | |||
T13422L | Talarozole (R enantiomer) | (R)-Talarozole,Talarozole R enantiomer | Others |
Talarozole R enantiomer is a potent and selective inhibitor of cytochrome P450 26-mediated breakdown of endogenous all-trans retinoic acid. | |||
T25716L | Liarozole HCl | R75251,Liarozole hydrochloride,R 75251,R-75251 | |
Liarozole HCl is a benzimidazole derivative with antineoplastic activity. As a retinoic acid metabolism blocking agent, liarozole inhibits CYP450-dependent all-trans-retinoic acid (ATRA)-4-hydroxylase, leading to an incr... | |||
T39703 | ATRA-biotin | ATRA-biotin,Biotin-ATRA-conjugate | |
ATRA-biotin is a biotin-conjugated form of all-trans retinoic acid (ATRA). It is utilized for the purpose of tracking ATRA within cells or specific tissues. | |||
T78102 | ER 50891 quarterhydrate | ||
ER 50891 quarterhydrate is a potent RARα (retinoic acid receptor α) antagonist that markedly diminishes the inhibitory effects of ATRA (all-trans retinoic acid) on osteoblastogenesis induced by BMP 2 (bone morphogenetic ... | |||
T36417 | Nargenicin | Antibiotic 47444 | |
Nargenicin is a macrolide antibiotic that selectively inhibits the growth of S. aureus, methicilin resistant S. aureus (MRSA), and M. luteus (MICs = 0.6, 0.3, and 2.5 μg/ml, respectively) over a panel of 11 Gram-positive... | |||
T35687 | Collismycin A | ||
Collismycin A is a bacterial metabolite originally isolated from Streptomyces that has diverse biological activities, including antibacterial, antiproliferative, and neuroprotective properties. It is active against a var... | |||
T35629 | ATRA-BA Hybrid | ||
ATRA-BA hybrid is a mutual prodrug form of all-transretinoic acid and butyric acid .1ATRA-BA hybrid is cleaved to release ATRA and BA in isolated mouse plasma. It inhibits the growth of MDA-MB-231 breast and PC3 prostate... |